Mag-Bind® TotalPure NGS offers an easy-to-use, reliable solution for the purification of both DNA and RNA for next-generation sequencing workflows with high recovery rates. Mag-Bind® TotalPure NGS is capable of selectively binding fragments depending on the reagent-to-sample ratio used, giving the user flexibility to perform left, right or double-sided size selection. This product is designed for both manual and fully automated purification of DNA and RNA samples, as well as for the purification of PCR products. The system combines Omega Bio-tek’s proprietary chemistries with reversible nucleic acid-binding properties of magnetic beads to selectively bind fragments and eliminate excess nucleotides, primers, and small, non-targeted products such as primer-dimers. Purified DNA and RNA is suitable for a variety of downstream applications such as NGS library preparation, microarrays, automated fluorescent sequencing and restriction enzyme digestion.
– No protocol change against major competitor
– NGS: Double or single-sided size selection
– DNA cleanup: PCR cleanup
– RNA cleanup: cDNA or RNA purification
– Manual or adaptable to most open-ended liquid handlers
– Significant cost savings
– 96- or 384-well formats
Protocols are available for the following automated platforms:
– Hamilton Microlab® STAR
– Hamilton Microlab® NIMBUS
– KingFisher™, BioSprint®, and MagMAX® 96